Glycoconjugates: advantages of conjugation analyzed fragment to fragment and determination of physicochemical properties useful for wide applications

Abstract

From now on, the brand new chemical products to be applied in health, bioremediation, industrial as well as technological fields necessarily are going to be related to sustainability, bioavailability, biodegradation and reduced toxicity, among other green characteristics coupled within the normal requirements for high performance substances. Hence, nowadays these are the worldwide and up to date optimization variables in molecular design. As has been often employed, a great number of industrial products and processes were obtained due to a mimetic approach to Mother Nature providing novelties. In this line the molecular design of compounds comprising natural building blocks such as amino acids, carbohydrates, lipids and nucleic acids is a key role in order to reach the desired sustainability of the new-line chemical products as well as to maintain the optimized usual process variables. Moreover, conjugated molecules formed by moieties from these four naturally occurring building blocks (amino acids, carbohydrates, lipids and nucleic acids) should result in advantageous physicochemical properties since by nature the conjunctions among these molecular bricks have been proven to work well in a broad diversity of experimental conditions, e.g. extreme variations of pH, salinity, sour, ionic strength, etc.