Título: | Angiotensinogen rs5050 germline genetic variant as potential biomarker of poor prognosis in astrocytoma |
Autor(es): | PERDOMO PANTOJA, ALEXANDER MEJIA PEREZ, SONIA ILIANA REYNOSO NOVERON, NANCY GOMEZ FLORES RAMOS, LILIANA SOTO REYES SOLIS, ERNESTO SANCHEZ CORREA, THALIA ESTEFANIA GUERRA CALDERAS, LISSANIA XIMENA CASTRO HERNANDEZ, CLEMENTINA VIDAL MILLAN, SILVIA SANCHEZ CORONA, JOSE TAJA CHAYEB, LUCIA GUADALUPE GUTIERREZ HERNANDEZ, OLGA CACHO DIAZ, BERNARDO ALVAREZ GOMEZ, ROSA MARIA GOMEZ AMADOR, JOSE LUIS OSTROSKY WEGMAN, PATRICIA CORONA VAZQUEZ, TERESITA HERRERA MONTALVO, LUIS ALONSO WEGMAN OSTROSKY, TALIA |
Temas: | Cerebro - Cáncer Oncología |
Fecha: | 2018 |
Editorial: | San Francisco CA. : Public Library of Science (PLoS) |
Citation: | PloS one, 13(11) 2018 : e0206590 |
Resumen: | Renin-angiotensin system (RAS) in brain cancer represents a scarcely explored field in neuro-oncology. Recently, some pre- and clinical studies have reported that RAS components play a relevant role in the development and behavior of gliomas. The angiotensinogen (AGT) rs5050 genetic variant has been identified as a crucial regulator of the transcription of AGT mRNA, which makes it a logical and promising target of research. The aim of this study was to determine the relationship between the AGT rs5050 genetic variant in blood with prognosis in astrocytoma. |
URI: | http://ilitia.cua.uam.mx:8080/jspui/handle/123456789/904 |
Aparece en las colecciones: | Artículos |
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Angiotensinogen rs5050 germline genetic variant as potential biomarker of poor prognosis in astrocytoma.pdf | 1.13 MB | Adobe PDF | Visualizar/Abrir |
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